Unlock the Benefits of Specialized Pro-Resolving Mediators for Health and Wellness

#biohacking #cellularhealth #chronicillness #fasting #mitochondria functionalmedicine functionalnutrition inflammation joyfuleating microbiome Jan 18, 2023

Do you suffer from chronic inflammation or other health conditions that are difficult to treat? If so, it's time to learn about specialized pro-resolving mediators. These powerful compounds have been shown in numerous studies to help reduce inflammation and even reverse certain diseases. In this article, we'll discuss what these specialized pro-resolving mediators are, the benefits they offer, how you can increase your intake of them, and the potential side effects associated with them. We hope this information will empower you on your journey toward reclaiming your health and wellness!

Table of Contents:

What are Specialized Pro-Resolving Mediators?

Specialized pro-resolving mediators (SPMs) are a group of molecules that play an important role in the body’s natural healing process. They are produced by cells in response to inflammation and help to reduce inflammation, restore balance, and promote tissue repair. SPMs can be found naturally occurring in certain foods as well as supplements.


SPMs are small molecules that act as messengers between cells and tissues to regulate the body’s inflammatory response. They work by binding to receptors on immune cells, which triggers a cascade of biochemical reactions that ultimately lead to resolution of inflammation. In addition, they have been shown to modulate gene expression related to inflammation and cell death pathways.


SPMs can be found naturally occurring in certain plant-based foods such as olive oil, nuts, seeds, legumes, fruits and vegetables. Additionally they can also be obtained from dietary supplements containing omega-3 fatty acids or other anti-inflammatory compounds like curcumin or resveratrol.

Role in Inflammation

The primary role of SPMs is reducing inflammation throughout the body by promoting resolution of acute inflammatory responses while preventing chronic low grade systemic inflammation associated with many diseases including heart disease and cancer. Studies have shown that these molecules may also protect against oxidative stress caused by free radicals, which can damage DNA leading to further health issues over time. Furthermore, SPMs may even enhance wound healing processes due to their ability to stimulate angiogenesis (the formation of new blood vessels).

Specialized Pro-Resolving Mediators are an important part of the body's natural inflammatory response and can be used to help reduce inflammation, chronic disease risk, and improve overall health. Next, we will discuss the benefits of utilizing Specialized Pro-Resolving Mediators in your healthcare plan.

"Inflammation got you down? Don't worry, specialized pro-resolving mediators are here to help. Get your SPMs from natural sources like olive oil and nuts or try a supplement for an extra boost. #SPMs #IntegrativeMedicine"Click to Tweet 

Benefits of Specialized Pro-Resolving Mediators

Specialized Pro-Resolving Mediators (SPMs) are naturally occurring molecules that help to reduce inflammation and promote healing. They play an important role in the body’s natural response to injury or infection, helping to restore balance and health.

Decrease Inflammation and Chronic Disease Risk: SPMs can help reduce inflammation by blocking pro-inflammatory pathways, reducing oxidative stress, and promoting tissue repair. This helps protect against chronic diseases such as heart disease, diabetes, cancer, Alzheimer's disease, arthritis, asthma and other autoimmune disorders. By decreasing inflammation in the body it can also improve overall wellbeing by increasing energy levels and improving sleep quality.

Improve Immune System Functioning: SPMs have been shown to modulate immune system functioning by activating anti-inflammatory responses while suppressing pro-inflammatory ones. This helps support a healthy immune system which is essential for preventing illness and maintaining good health over time. Additionally they may also help increase resistance to infections by stimulating production of antibodies which fight off invading pathogens more effectively than before.

The presence of SPMs has been linked with improved wound healing processes due to their ability to stimulate cell growth at sites of injury or infection as well as reduce swelling around damaged tissues, which can significantly slow down recovery times if left untreated. Furthermore, they may also aid in the regeneration of nerve cells following trauma or damage caused by stroke or other neurological conditions, making them beneficial for those suffering from long-term disabilities associated with these issues too.

The benefits of specialized pro-resolving mediators are numerous, from decreasing inflammation and chronic disease risk to improving immune system functioning and enhancing healing processes. By learning how to increase intake of SPMs through dietary sources, supplements, and lifestyle changes, you can further support your health journey.

Don't let inflammation get you down. Specialized Pro-Resolving Mediators can help reduce chronic disease risk, improve immune system functioning and even aid in wound healing. #SPMsForLifeClick to Tweet 

How to Increase Intake of Specialized Pro-Resolving Mediators?

Dietary Sources of SPMs: Specialized pro-resolving mediators (SPMs) are a type of lipid molecule that helps the body fight inflammation and heal itself. Increasing intake of these molecules can help to reduce chronic inflammation and improve overall health. Dietary sources of SPMs include fatty fish, such as salmon, mackerel, sardines, herring, anchovies; plant oils like flaxseed oil; nuts and seeds; olives; avocados; egg yolks; dairy products like yogurt or cheese made from grass-fed cows’ milk.

Supplements Containing SPMs: There are also several supplements available on the market that contain concentrated amounts of SPMs. These supplements typically come in liquid form and can be taken orally or applied topically to affected areas for localized relief from pain and inflammation. Common ingredients found in these supplements include omega-3 fatty acids (EPA & DHA), gamma linolenic acid (GLA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), alpha lipoic acid (ALA) and astaxanthin.

Increasing your intake of specialized pro-resolving mediators through dietary sources, supplements, and lifestyle changes can help you reclaim your health and wellness. However, it is important to understand the potential side effects before taking any action.

Key Takeaway: SPMs can help reduce chronic inflammation and improve overall health. To increase intake of these molecules, one should incorporate dietary sources such as fatty fish, plant oils, nutsseeds, olives, avocados and egg yolks into their diet or take supplements containing omega-3 fatty acids (EPA & DHA), GLA, EPA, DHA, ALA and astaxanthin.

Potential Side Effects of Specialized Pro-Resolving Mediators?

Allergic Reactions and Intolerance Symptoms: It is possible to experience an allergic reaction or intolerance symptoms when taking SPMs. Allergic reactions can range from mild skin rashes to more severe respiratory issues, depending on the individual's sensitivity. In addition, some people may experience digestive discomfort such as nausea, vomiting, and diarrhea after consuming SPMs. If any of these symptoms occur, it is important to stop taking the supplement immediately and consult a doctor for further advice.

Interactions with Other Medications or Supplements: Specialized pro-resolving mediators can interact with other medications or supplements that are being taken at the same time. Therefore, it is important to discuss all current medications and supplements with a healthcare provider before beginning an SPM regimen in order to avoid potential interactions that could be harmful.

Taking too much of an SPM supplement can lead to overdose risks which include headaches, dizziness, confusion, fatigue and even seizures in extreme cases. To avoid this risk it is important not to exceed recommended dosages without consulting a doctor first as they will be able to provide tailored advice based on individual needs.

Don't be a pill-popper. Before taking specialized pro-resolving mediators, make sure to talk to your doctor about any potential interactions or overdose risks. #IntegrativeMedicineClick to Tweet 

FAQs in Relation to Specialized Pro-Resolving Mediators

What do specialized pro-resolving mediators do?

They help promote resolution of inflammation, reduce tissue damage and restore homeostasis. SPMs act as messengers between cells and organs, helping them communicate with each other to coordinate healing responses. They also have anti-inflammatory properties which can help reduce pain and swelling associated with chronic conditions such as arthritis or autoimmune diseases. In addition, they may improve overall health by promoting healthy cell growth and regeneration while suppressing damaging processes like oxidative stress.

What are SPMs for inflammation?

SPMs, or Standardized Protocols of Medicine, are evidence-based approaches to treating inflammation. These protocols involve a combination of lifestyle changes such as diet and exercise modifications, stress reduction techniques, nutritional supplementation, herbal remedies and other therapies that have been proven to reduce inflammation. Additionally, SPMs may include the use of medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids for more severe cases. By following an integrative approach to health care with these SPMs for inflammation, individuals can improve their overall well-being and reduce symptoms associated with chronic inflammatory conditions.

What are pro-resolving lipids?

Pro-resolving lipids are specialized molecules produced by the body that help to resolve inflammation and promote healing. They play an important role in the body's natural ability to heal itself, reduce pain, and restore balance. Pro-resolving lipids have been shown to be beneficial for a variety of chronic diseases including cardiovascular disease, diabetes, arthritis, autoimmune disorders and more. Additionally, they can improve overall health by promoting healthy cell growth and metabolism.

What are the side effects of SPMs?

SPMs are generally well tolerated and have few side effects. Most commonly reported are mild gastrointestinal symptoms such as nausea, diarrhea, or abdominal discomfort. Rarely, some people may experience headaches or dizziness. It is important to note that SPMs should not be taken if you have an allergy to shellfish as it contains a derivative of shrimp and crab shells. Additionally, pregnant women should consult their doctor before taking this supplement due to potential risks for the fetus.


In conclusion, specialized pro-resolving mediators are a powerful tool for reducing inflammation and reversing chronic disease. They can be found in many natural sources such as certain fruits, vegetables, herbs, spices, and oils. Increasing the intake of these substances can help to reduce inflammation and improve overall health. However, it is important to note that there may be potential side effects associated with consuming too much of these specialized pro-resolving mediators so it is best to consult with your healthcare provider before making any changes to your diet or lifestyle.

It is time to take action and find solutions that will help us better understand the role of specialized pro-resolving mediators in integrative medicine. Through research, we can uncover new ways to use these powerful tools as part of our holistic approach toward health and wellness. Let's work together to unlock their potential for improved patient outcomes!

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